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BACKGROUNDS. Numerous scientific and clinical findings confirm that pain slows down the process of wound healing. In our previously published research, we presented a prototype of an analgesic wound dressing with two analgesics: lidocaine, a local anesthetic with immediate onset of effect for alleviation of pain caused by wound care, and diclofenac for further reduction of the pain present due … Preberite več >>

Anti-neutrophil cytoplasmic antibody vasculitis is a vasculitis of small vessels and can cause damage to many organs, most commonly the kidneys, upper and lower respiratory tract, gastrointestinal tract, skin, and nervous system. It is characterized by IgG antibodies that are directed against components of the cytoplasm of neutrophils. According to the immunofluorescence pattern, anti-neutrophil cytoplasmic antibodies are divided into antibodies … Preberite več >>

Haemostasis is a process in which a blood clot is formed in the wall of a damaged blood vessel. Haemostasis thus prevents blood loss while maintaining blood fluidity within the vascular system. The process includes a balanced cooperation of the elements of the vessel wall, blood platelets, and coagulation factors from blood plasma and damaged tissue cells. Haemostasis can be … Preberite več >>

Currently we do not yet know the populational burden of work-related and occupational neurological diseases. There is, however, scientific evidence for correlations between chemical, biological, and physical agents at workplace and different acute, subacute, and chronic neurological diseases and injuries. Exposure to pesticides and manganese is a risk factor for development of parkinsonism. Inhalation of diesel fumes, especially in professional … Preberite več >>

Familial hypercholesterolemia is a common genetic disorder. It is characterised by high cholesterol levels and early cardiovascular disease. With systematic biochemical testing in children, we can establish an early diagnosis of hypercholesterolemia. Furthermore, high risk individuals can be identified by measuring morphological and functional properties of arterial wall together with endothelial function assessment. In hypercholesterolemic children, early non-pharmacological (life-style change) … Preberite več >>

Prevalence and symptoms of musculoskeletal disorders increases with age due to repetitive load and degenerative changes. However, they are becoming more common even at a young age. In children, one of the ergonomic risk factors for developing pain is the use of school bag. The purpose of this literature review was to evaluate the scientific evidence on the possible association … Preberite več >>

Graves’ disease is an autoimmune thyroid disorder and the most frequent cause of hyperthyroidism in Slovenia. Antithyroid drugs are usually used as the first line of treatment. However, in rare cases they cause agranulocytosis with life-threatening neutropenia. We present a case of a patient who was simultaneously diagnosed to have Graves’ disease as well as moderate neutropenia, which was most … Preberite več >>

Tinea faciei is a superficial dermatophyte infection limited to the glabrous skin of the face. It is often seen in pediatric patients. Although the infective organisms and treatments are the same as for other superficial fungal infections, it is frequently misdiagnosed and modified or aggravated by administration of topical or systemic corticosteroids progressing to tinea incognito. We present a case … Preberite več >>

Despite its potential to spread to the brain, metastatic melanoma has been rarely described within the hypothalamic-pituitary axis especially isolated metastases are extremely rare. Metastases to this area most frequently appear in patients with carcinomas of the breast or lungs and are rarely symptomatic, most often patients present with central diabetes insipidus. In the present paper, we report a case … Preberite več >>