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Schizophrenia and bipolar disorder are mental disorders that pose a real problem to the public health care system. Early diagnosis and treatment is instrumental in a relatively good management and control of these two diseases. Second-generation antipsychotics increase the likelihood of selecting the right, optimal medicine, which enables effective treatment at reduced strength and frequency of adverse reactions. We conducted … Preberite več >>

Choanal atresia is a rare congenital malformation which occurs in every 5000 to 8000 live newborns. Clinically, it may present as an isolated form or in association with other malformations. In most cases, the cause is not found, but some are associated with a genetic mutation or the use of certain drugs against hyperthyroidism during pregnancy. The dominant clinical picture … Preberite več >>

The etiology and pathophysiology of spontaneous cervical artery dissection are largely unknown. Its etiology is likely multifactorial, and primary arteriopathy is most probably involved. An association with migraine has also been suggested, but it remains unproven. A case report of a patient with migraine and spontaneous bilateral internal carotid artery dissection is presented.… Preberite več >>

Keratoacanthoma is an epidermal malignancy, which histopathologically resembles to squamous cell carcinoma. Multiple keratoacanthomas are a heterogeneous group of inherited or acquired disorders. Several different mechanisms may be responsible for their development, including UV radiation, ionizing radiation, viruses (human papillomavirus), and chemical carcinogens (tar), as well as certain immunologic and genetic factors. The article is a report on three patients … Preberite več >>

Despite profound advances in the treatment of ischemic heart disease with medications or invasive procedures during the past 30 years, ischemic heart disease remains the main cause of mortality and morbidity in developed countries. Elevated resting heart rate is a well-known and easily measured risk factor, but too little attention is paid to decreasing it. A person’s heart rate depends … Preberite več >>

In view of increased prevalence of heart failure and the persistent unacceptably high morbidity and mortality associated with this condition despite current pharmacological treatments, novel therapeutic approaches have been sought. Cardiac resynchronization therapy offers proven benefit to patient with medically refractory symptomatic heart failure, severe left ventricular dysfunction (ejection fraction < 35%), and wide QRS complex (> 120ms). This treatment … Preberite več >>

In order to make a diagnosis in a patient with a gynecologic disease, detailed history taking and clinical examination are the first steps to patient management, while cytological diagnostic methods (including cervical smear), colposcopy, and biopsy techniques established in
gynecology come next. Cervical smear screening is one of the most successful screening tests used in medicine.… Preberite več >>

The treatment of liver injuries is a special challenge for surgeons. We have modern treatment techniques, but severe liver injuries still represent a high percentage of the overall mortality rates. Blunt trauma in motor vehicle accidents is the most common cause of liver injury. Its clinical picture depends on the degree of injury and the number of any other, associated … Preberite več >>

Amphetamine consumption is highly spread throughout the world, especially in the Unites States of America, Australia and Asia. In Slovenia, the consumption of amphetamines and methamphetamines is not so spread and, further more, it is also not increasing. Amphetamines cause a euphoric state. Their effects are an immediate consequence of an increased release of dopamine, serotonin and noradrenaline in synapses … Preberite več >>

It has been a century since the Brazilian physician Carlos R. J. Chagas first described the basic morphology and life cycle of the American trypanosome, a parasite which causes Chagas disease. Chagas disease is a zoonosis caused by Trypanosoma cruzi. Trypanosoma cruzi is found mostly in blood-sucking triatomine insects and small mammals in areas ranging from the southern and southwestern … Preberite več >>

BACKGROUND. Impacted maxillary canines occur in 2% of the population. Extraction of a deciduous canine is a possible preventive measure and is most successful in patients under 13 years of age. Later on, complex treatment is needed. Our aim was to collect epidemiological data regarding impacted maxillary canines in the Slovenian population. Emphasis was on the subject’s age at the … Preberite več >>